International Journal of Science , Engineering and Management (IJSEM)

Monthly Journal for Science , Engineering and Management

Volume3,February 2018,

Topic : A Review on Medicinal Importance and Synthesis of benzothiazolo-[2, 3b]-quinazolin-1-one Derivatives via Multi-Component Reactions

Authors:Satish A. Dake || Ashok R. Yadav, Changdev V. Mane, Jyoti M. Weldode, Rajendra P. Pawar

Abstract:Synthesis of benzothiazolo-[2, 3b]-quinazolin-1-ones and their derivatives offered important biological and pharmaceutical applications in Chemistry research field. Multi-component reactions in recent days gained a new aspect in designing methods to produce sophisticated libraries of biologically active heterocyclic compounds. Green Chemistry has become a powerful tool in Chemistry in the last decade and recent areas of interest are the production of organic bioactive molecules via MCRs with an environmentally friendly solvent system such as water, ionic liquids etc. Multi-component methodologies contribute remarkable advantages over conventional reactions due to maintaining their atom economy, convergence, easy work-up procedure, structural multiplicity and short reaction time. The present review expresses various synthetic methods and medicinal importance of benzothiazolo-[2,3b]-quinazolin-1-ones and their derivatives..

Keywords: Biological activity, [2, 3b]-quinazolin-1-ones, multi-component reactions, organic transformations, synthesis

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DOI: 01.1617/vol5/iss2/pid05173


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Dr.Muhammad Ishtiaq,
Mirpur University of
Science & Technology,
Mirpur, Azad Kasmir.

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IMPACT FACTOR: 2.7

ISSN(Online): 2456-1304

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Thomson Reuters ID : q-6288-2016.
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Journal Code : IJSEM
Electronic ISSN : 2456-1304
Impact Factor : 2.7
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