International Journal of Science , Engineering and Management (IJSEM)

Monthly Journal for Science , Engineering and Management

Volume1,June 2016,

Topic : Antimicrobial, Antioxidant Activity and Phytochemical Analysis Of An Endophytic Fungi Penicillium Oxalicum Isolated from a Gymnosperm Tree Cupressus Torulosa D.Don. Of Garhwal Region

Authors:Rinky Bisht || Arun Bhatt and Pavan Kumar Agarwal

Abstract:Penicillium oxalicum was isolated as an endophyte from leaves of medicinal plant, Cupressus torulosa. Chloroform extract of the P. oxalicum was evaluated for antimicrobial (antibacterial and antifungal) and antioxidant activity. Chloroform extract was effective against Escherichia coli, Staphylococcus aureus and Salmonella typhi. Fungal crude extracts showed inhibitory activity against pathogenic microorganisms, with an average zone of inhibition varied between 9 mm to 10 mm, and the largest zone was of 10 mm against E. coli and B.subtilis. The antifungal activity of fungal crude extract was checked against the pathogens Fusarium solani and Fusarium oxysporim. P. oxalicum extract show maximum inhibition of 83.33% against F.oxysporium. Minimum inhibitory concentration (MIC) of chloroform extract evaluated by tube broth dilution method was recorded as 12.5mg/mL against S.typhi and 6.25mg/mL for B. subtilis and S.aureus. Phytochemical analysis revealed the presence phenolic compounds and anthraquinones. P. oxalicum was also examined for in vitro antioxidant activity by DPPH radical scavenging assay. The chloroform extract of the fungal endophytes showed potent antioxidant activity with IC50 value of 17.47?g/mL compared to the IC50 value of standard ascorbic acid, 9.0mg/mL..

Keywords: Endophytic fungi, Penicillium oxalicm, Antimicrobial activity

Download Paper

DOI: 01.1617/vol1iss2pid0010022

Related Articles

Relation between Storage Volume and Erosion Control Performance of Woven Geomesh

Authors: Vinay Kumar Midha || Suresh Kumar S

Doi : 01.1617/vol1iss2pid0010002

Volume1 ,June 2016.

Mathematical Modelling Of H1N1

Authors: Fenny J. Narsingani || Dr. M.B.Prajapati, Dr. P. H. Bhathawala

Doi : 01.1617/vol1iss2pid0010003

Volume1 ,June 2016.

Exact Zero-Divisor Graph

Authors: Premkumar T. Lalchandani || Premkumar T. Lalchandani

Doi : 01.1617/vol1iss2pid0010004

Volume1 ,June 2016.

Synthesis, Characterization and Transparency of Graphene Oxide Nano Particles Prepared by Modified Hummerís Method

Authors: Reeta Kumar || Megha Shrivastava,Fozia Z. Haque

Doi : 01.1617/vol1iss2pid0010010

Volume1 ,June 2016.

Room Light Anodization of N-Type Silicon and Study of Its Photoluminescence

Authors: MeghaShrivastava || ReetaKumari,Fozia Z. Haque

Doi : 01.1617/vol1iss2pid0010011

Volume1 ,June 2016.

Nano Science and Nano Technology

Authors: Dr. Awadhesh Prasad ||

Doi : 01.1617/vol1iss2pid0010019

Volume1 ,June 2016.

Preliminary Screening for Laccase Producing Endophytic Fungi from Cupressus Torulosa D.Don

Authors: Sheetal Chanyal || Pavan Kumar Agrawal

Doi : 01.1617/vol1iss2pid0010021

Volume1 ,June 2016.

Biodegradation of Polycyclic Aromatic Hydrocarbon by Alternaria Alterna

Authors: Jyoti Verma || Deeksha Sharma, Pavan Kumar Agarwal

Doi : 01.1617/vol1iss2pid0010023

Volume1 ,June 2016.

A Study to Assess the Surgical Safety Compliance in an Operation Theater of Tertiary Care Hospital

Authors: Mamtha .M || Sarala K. S,Nagesha H.N

Doi : 01.1617/vol1iss2pid0010025

Volume1 ,August 2016.

Pesticide Residues due to Agricultural Practices and its Human Health Effects

Authors: Dev Kumari || Siby John

Doi : 01.1617/vol1iss2pid0010026

Volume1 ,August 2016.


Editor Image

Dr.Muhammad Ishtiaq,
Mirpur University of
Science & Technology,
Mirpur, Azad Kasmir.

View more


ISSN(Online): 2456-1304

Google Scholar Profile

Thomson Reuters ID : q-6288-2016.
ORCiD Research ID : 0000-0001-9540-6799

All Issues


Copy-right Form Paper Template


Journal Code : IJSEM
Electronic ISSN : 2456-1304
Impact Factor : 2.7
Frequency : Monthly
Contact :

IFERP Other Journals



Social Media