Date of Publication :15th May 2024

Abstract:Diseases and deaths caused by pathogenic microorganisms are a serious problem worldwide. As a result of the problems caused by the unnecessary and unconscious use of antibiotics and the realization of the side effects of synthetic antimicrobials, there was a need to discover new antimicrobials obtained from natural sources. Lemna minor macrophyte has strong antimicrobial and antioxidant properties due to its secondary metabolites. Because of this feature, it has been used in traditional treatments for years. This study aimed to investigate the antimicrobial activity of L. minor against 11 different microorganisms (E. coli ATCC 25922, S. aureus ATCC 25923, S. aureus MRSA, P. aeruginosa ATCC 27853, B. cereus ATCC 6633, S. epidermidis ATCC 12228, L. monocytogenes, K. pneumoniae, S. infantis, S. typhimurium, Enterococcus faecalis bacteria and C. albicans ATCC 10231). L. minor was extracted by microwave and then lyophilized. The activities of lyophilized extracts were investigated by Minimal Inhibitory Concentration (MIC)( 16-1000 μg/ml) and agar diffusion (250-500 μg/ml) methods. In general, it has been determined that concentrations of 250-500 μg/ml cause inhibition of all pathogens. The highest activity was determined K. pneumoniae (62.5 μg/ml) and P. aeruginosa (125 μg/ml).

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