Open Access Journal

ISSN : 2456-1304 (Online)

International Journal of Engineering Research in Electronics and Communication Engineering(IJERECE)

Monthly Journal for Electronics and Communication Engineering

Open Access Journal

International Journal of Science Engineering and Management (IJSEM)

Monthly Journal for Science Engineering and Management

ISSN : 2456-1304 (Online)

Synthesis and biological evaluation of newly synthesized Flavones

Author : Shradha Binani 1 Lavanya Nagamalla 2 Pravin Bodkhe 3 R.V.Joat 4

Date of Publication :14th February 2018

Abstract: Flavones are bioactive substances, essential for human growth and development. It is naturally available in cereals and herbs. It is synthesized in excellent yield by Baker-Venkataraman reaction for formation of 1, 3-diketone by using substituted acetophenone and benzoyl chloride in presence of dry pyridine. The structures of newly synthesized compounds have been confirmed on the basis of elemental analysis, UV, IR, H-NMR spectral data and evaluated for biocidal activity on the basis of inhibition of growth of bacteria and fungus compared with a standard drug

Reference :

    1. Weidenbörner M & Jha H C, Pestic Sci38, 1993, 347.
    2. Silva A M, Weidenbörner M & Cavaleiro J A S, Mycol Res102, 1998, 638
    3. Wu E S C, Loch J T, Toder B H, Borrelli A R, Gawlak D, Radov L A & Gensmantel N P, J Med Chem35, 1992, 3519.
    4. Wolfman C, Viola H, Marder M, Wasowski C, Ardenghi P, Izquierdo I, Paladini A C & Medina J H, Eur J Pharmacol318,1996, 23.
    5. Akama T, Ishida H, Kimura U,Gomi K, Saito H, Fuse E, Kobayashi S, Yoda N & Kasai M, J Med Chem40, 1997, 1894.
    6. Gee J M & Johnson I T, Curr Med Chem8, 2001, 1245.

Recent Article