Author : K.F.Roselin 1
Date of Publication :20th April 2018
Abstract: Oxidative stress is an imbalance between the production of free radicals and the ability of the body to counteract or detoxify their deleterious effects by way of neutralisation by antioxidants. An antioxidant is a molecule that inhibits the oxidation of other molecules and protects the body cells and tissues from damages caused by free radicals and ROS. They are released from the diet that we take and enter the cells through the blood stream and prevent damage to cells by cleaning up. Methods like DPPH, Hydroxyl, ABTS, superoxide, and reducing power was used to evaluate free radical scavenging activities of various concentrations of different extracts of Didemnum psammathodes using ascorbic acid and trolox as standard. The radical scavenging effect was found to increase with increasing concentrations. Ethanol extract (108.26, 112.15) showed highest DPPH, hydroxyl radical scavenging activity whereas, in ABTS and superoxide methanol extract exhibited highest (138.16, 126.81). Methanol and ethanol extracts exhibited higher reducing ability among the solvent tested. The results revealed that the extracts possess potential reducing power and hence antioxidant activity compared to standard.
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