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ISSN : 2456-1304 (Online)

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Open Access Journal

International Journal of Science Engineering and Management (IJSEM)

Monthly Journal for Science Engineering and Management
Call For Paper : Vol 11, Issue 08, August 2024

ISSN : 2456-1304 (Online)

Call for Paper

Vol 11, Issue 08, August 2024

Indexing

Current Concept and Research Progress of Pre-Eclampsia (Early-Onset and Late-Onset Pre-Eclampsia)

Author : Binod Chaudhary 1 Jifang Shi 2

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Date of Publication :16th September 2022

Abstract: Pre-eclampsia is a syndrome that belongs to the group of hypertensive disorders of pregnancy. It is a multi-organ disease and can affect the kidney, liver, brain and the blood clotting system [1,2]. Pre-eclampsia is one of the most common causes of maternal and fetal morbidity and mortality [3]. Pre-eclampsia is defined as new-onset hypertension developed after 20 weeks of gestation (systolic or diastolic blood pressure ≥140 and/or ≥90 mmHg, respectively, measured at least two occasions, 4 hour to 1 week apart) and proteinuria(≥300 mg in a 24- hour urine collection, or two random urine specimens obtained 4 hours to 1 week apart containing≥1+ by dip stick or one dipstick demonstrated ≥2+ protein)[22,23]. Mild pre-eclampsia was diagnosed as pre-eclampsia was systolic blood pressure <160 mmHg, diastolic blood pressure <110 mmHg, platelet count≥100,000 per mm3, non-elevated liver enzymes, absence of renal insufficiency, pulmonary edema, cyanosis, new-onset cerebral/visual disturbances, and/or right upper quadrant or epigastric pain[24,25]. Severe pre-eclampsia is diagnosed as pre-eclampsia with systolic blood pressure ≥160 mmHg, or diastolic blood pressure ≥110 mmHg, platelet count <100,000 per mm 3, elevated liver enzymes, renal insufficiency, pulmonary edema or cyanosis, new-onset cerebral/visual disturbances, and/or right upper quadrant or epigastric pain [24,25]. A major advance in the classification of pre-eclampsia is its subdivision into early-onset and late-onset pre-eclampsia[26,27]. Especially, early-onset and late-onset pre-eclampsia have a serious threat to the maternal and neonatal lives, and in the clinical practice, it is of great difficulties and challenging in its treatment. Therefore, it is of great importance to pay enough attention to early-onset and late-onset pre-eclampsia. According to the statistics of recent years in China, the prevalence of pre-eclampsia has become less due to increase in attention paid to the pregnant women with the hypertensive disorder and in the maternity examination during their period of antenatal check-up

Reference :

    1. Roberts JM, Speer P. Antioxidant therapy to prevent preeclampsia Semin Nephrol 2004;24:557-64.
    2. ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002. American College of Obstetricians and Gynecologists. Int J Gynecol Obstet 2002;77:67-75.
    3. Robert JM, Pearson GD, Cutler JA, Lindheimer MD.Summary of the NHLBI Working Group on research on hypertension during pregnancy. Hypertens Pregnancy 2003;22:109-27.
    4. Wallis AB, Hsia J, Atrash HK(2008) Secular Trends IN the rates of pre-eclampsia, eclampsia and gestational hypertension, United States, 1987- 2004. Am J Hypertens 21:521-526 .
    5. Kuklina EV, Ayala C, Callaghan WM (2009).Hypertensive disorders and severe obstetric morbidity in the United States. Obstet Gynecol 113;1299-1306. 
    6. Hutcheon JA, Lisonkova S, Joseph KS(2011) Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy.Best Pract Res Clin Obstet Gynaecol 25:1299-1306.
    7. Paruk, Moodley J (2000) Maternal and neonatal outcome in early- and late-onset-pre eclampsia. Semin Neonatal 5:197-207. 
    8. MacKay AP, Berg CJ, Atrash HK (2001)Pregnancy-related mortality pre-eclampsia and eclampsia. Obstet Gynecol 97;533-538. PMOD;11275024.
    9. Berg CJ.MackayAP, QIN C, CallaghanWM(2009)Overview of maternal morbidity during hospitalization for labor and delivery in the United States:1993-1997 and 2001 -2005. Obstet Gynecol 113:1075-1081.
    10. Stekkinger E, Zandstra M, Peeters LL, Spaanderman ME(2009)Early-onset pre-eclampsia and the prevalence of postpartum metabolic syndrome. Obstet Gynecol 114:1076-1084. 
    11. Smith GC, Pell JP, WalshD (2001) Pregnancy complications and maternal risk of ischemic heart disease: a retrospective cohort study of 129,290 births. Lancet 357;2002-2006.
    12. Bellamy L, Casas JP, Hingorani AD, Williams DJ(2007) Preeclampsia and the risk of cardiovascular disease and cancer in later life: systemic review and meta-analysis. BMJ 335:974. 
    13. Schutte JM, Steeger EA, Schuitemaker NW, Santema JG, de Boer K, Pel M, et al. (2010) Rise in maternal mortality in the Netherlands. Bjog 117:399-406.
    14. Hnat MD, Sibai BM, Caritis S, Haunt J, Lindheimer MD, MacPherson C, et al. (2002) Perinatal outcome in women with recurrent preeclampsia compared with women who develop preeclampsia as nulliparas. Am J Obstet Gynecol 186:422-426. PMID:112904601
    15. Madazli R, Yuksel MA, Imamoglu M, Tuten A, Oncul M, Aydin B, et al. 92014) Comparision of clinical and perinatal outcomes in early- and late-onset preeclampsia. Arch Gynecol Obstet 290:53-57.
    16. Sanro L, Maruotti GM, Saccone G, Sirico A, Mazzarelli P(2015) Pregnancy outcome in proteinuria-onset and hypertension-onset preeclampsia.Hypertens Pregnancy 34:284-290
    17. Adams T, Yeh C, Bennett-Kinzler WL(2014)Long-term maternal morbidity and mortality associated with the ischemic placental disease. Semin Perinatal 38:146-150. 
    18. Lisonkova S, Sabr Y, Mayer C, Young C, Skoll A, Joseph KS(2014) Maternal morbidity associated with early-onset and late-onset preeclampsia. Obstet Gynecol 124:771-781. 
    19. Ozimek JA, Eddins RM, Greene N,karagyozyan D, Pak S, Wong M, et al. (2016) Opportunities for improvement in care among women with severe maternal morbidity. Am J Obstet Gynecol 215:509e501-506.
    20. [20] Brosens I, Pijnenborg R, Vercruysee L, Romero R(2011) The ‘Great Obstetrical Syndromes‘ are associated with disorders of deep placentation. Am J Obstet Gynecol 204:193-201.
    21. Clinical analysis of 101 cases of early-onset severe preeclampsia, such as Yuejin, Meili and Shelan 2013:01(15):234-340.
    22. Soto E, Romero R, Kusanovic JP, Ogge G, Hussein Y, Yeo L, et al. (2012)Late-onset ore eclampsia is associated with an imbalance of angiogenic and anti-angiogenic factors in patients with and without placental lesions consistent with maternal under perfusion. J Maternal-Fetal Neonatal Med 25:498-507.https://doi.org/10.3109/14767058.2011.591461 PMID:21867402.
    23. 2002) ACOG practice bulletin.Diagnosis and management of pre-eclampsia and eclampsia. Number 33, January 2002. Obstet Gynecol 99:159-167. PMID: 16175681.
    24. Chaiworapongsa T, Chaemsaithong P, Yeo L, Romero R(2014)Pre-eclampsia part-1; current understanding of its pathophysiology. Nat Rev Nephrol 10:466-480. 
    25. Tranquilli AL, Brown MA, Zeeman GG, Dekker G, Sibai BM (2013) The definition of severe and early onset-onset pre-eclampsia. Statements from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Pregnancy Hypertens 3:44-47. 
    26. Jelin AC, Cheng YW, Shaffer BL, Kaimal AJ, Little SE, Caughey AB (AB (2010) Early-onset pre-eclampsia and neonatal outcomes. J Matern Fetal Neonatal Med 23:389-392. 
    27. Espinoza J, Romero R, Nien JK, Gomez R, Kusanovic JP, Goncalves LF, et al. (2007) Identification of patients at risk for early-onset and/or severe preeclampsia with the use of uterine artery Doppler velocimetry and placental growth factor. Am J Obstet Gynecol 196;326.e321-313.
    28. von Dadelszen P, Magee LA, Roberts JM (2003).Subclassification of preeclampsia. Hypertens Pregnancy 22:143-148. https://doi.org/10.1081/PRG-120021060 PMID: 12908998.
    29. Valensise H, Vasapollo B, Gagliardi G, Novelli GP (2008) Early and late preeclampsia: two different maternal hemodynamic states in the latent phase of the disease. Hypertension 52:873-880. 
    30. Kenneth L, Hall DR, Gebhardt S, Grove D(2010) Late-onset pre-eclampsia is not an innocuous condition. Hypertens Pregnancy 29:262-270. 
    31. Moldenhauer JS, Stanek J, Warshak C, Khoury J, Sibai B (2003) The frequency and severity of placental findings in women with pre-eclampsia are gestational age-dependent. Am J Obstet Gynecol 189:1173-1177 PMID: 14586374.
    32. Sebire NJ, Goldin RD, Regan L(2005) Term pre-eclampsia is associated with minimal histopathological placental features regardless of clinical severity. J Obstet Gynaecol 25:117-118. 
    33. van der Merwe JL, Hall DR, Wright C, Schubert P, Grove D(2010) Are early and late pre-eclampsia distinct subclasses of the disease_ what does the placenta reveal? Hypertens Pregnancy 29:45-467.  
    34. Ogge G, Chaiworapongsa T, Romero R, Hussein Y, Kusanovic JP, Yeo L, et al. (2011) Placental lesions associated with maternal under perfusion are more frequent in early-onset than in late-onset preeclampsia. J Perinat Med 39:641-652. 
    35. Mifsud W, Sebire NJ (2014) Placental pathology in early-onset and late-onset fetal growth restriction. Fetal Diagn Ther 36:117-128.
    36. Odegard RA, Vatten LJ, Nilsen ST, Salvesen KA, Austgulen R (2000) Preeclampsia and fetal growth. Obstet Gynecol 96:950-955. PMID: 11084184.
    37. Yu CK, Khouri O, Onwudiwe N, Spiliopoulos Y, Nicolaides KH(2008) Prediction of pre-eclampsia by uterine artery Doppler imaging; relationship to gestational age at delivery and small-for-gestational-age. Ultrasound Obstet Gynecol 31:310-313. 
    38. Jelin AC, Cheng YW, Shaffer BL, Kaimal AJ, Little SE, Caughey AB(2010). Early o-onset preeclampsia and neonatal outcomes .J Matern Fetal Neonatal Med 23:389-392. 
    39. Lisonkova S, Joseph KS (2013). Incidence of preeclampsia: risk factors and outcomes associated with early-versus late-onset disease. Am J Obstet Gynecol 209:544.e541-544.e512.
    40. Tobinaga CM, Torloni MR, Gueuvoghlanian-Silva BY, Pendeloski KP, Akita PA, Sass N, et al. (2014) Angiogenic factors and uterine Doppler velocimetry in early-and late-onset preeclampsia. Acta Obstet Gynecol Scand 93:469-476. 
    41. Muresan D, Rotar IC, Stamatian F (2016) The usefulness of fetal Doppler evaluation in early versus late intrauterine growth restriction. Review of the literature. Med Ultrason 18:103-109. 
    42. Vatten LJ, Skjaerven R (2004) is preeclampsia more than one disease? Blog 111:298-302. PMID: 15008762.
    43. Eskild A, Romundstad PR, Vatten LJ (2009) Placental weight and birth weight: does the association differ between pregnancies with and without pre-eclampsia? Am J Obstet Gynecol 201:595e591-595.
    44. Espinoza J, Lee W, Martin SR, Belfort MA(2014) Customised growth curves for identification of large-for-gestational-age neonates in pre-eclamptic women.Ultrasound Obstet Gynecol 43: 165-169. PMID: 23703927.
    45. Rasmussen S, Irgens LM, Espinoza J (2014). Maternal obesity and excess of fetal growth in pre-eclampsia. BJOG 121:1351-1357. 
    46. Maternal morbidity associated with early-onset and late-onset preeclampsia. Lisonkova S, Sabr Y, Mayer C, SKOLL A, Joseph KS. Obstet Gynecol 2014 Oct;124(4):771-81.doi:10.1097/AOG.0000000000000472.
    47. An analysis of the difference between early-onset and late-onset preeclampsia. Li Xi, Guo PL, Xue Y, Gou WL, Tong M, Chen Q. Pregnancy Hypertens 2016 Jan;6(1):47-52.doi:10.1016/j.preghy.2015.12.003. Epub 2015 Dec 17.
    48. Early-onset and late-onset preeclampsia: Clinicopathologic study of 178 placentas. Zhang X, Jia H, Wang Y, Xie J, Gu Y. Zhonghua Bing Li Xue Za Zhi 2015 Dec; 44(12):879-83.
    49. A comparative study of clinical indicators of early-onset and late-onset severe pre-eclampsia by Huang Ting. Men Shengyou and Department of Obstetrics and Gynecology 2017:9(8):112-214.
    50. Comparison of indications of Pregnancy Termination and Prognosis of mothers and neonates in early-and-late-onset pre-eclampsia. Ni Y, et al. Hypertens Pregnancy 2016 Aug;35(3):315-22.doi:10.3109/10641955.2016.1143486. Epub 2016 Mar 1.
    51. Li Xuelan: Analysis of delivery mode and maternal and infant outcomes of early-onset and late-onset severe preeclampsia; Chinese Journal of Practical Gynecology and OObstetrics 2012:04(02)450467;”1”.
    52. Placental pathology in early-onset and late-onset fetal growth restriction. Mifsud W, Sebire NJ. Fetal Diag Ther, 2014;36(2):117-28.doi:10.1159/000359969. Epub 2014Feb 21.
    53. Fan Cuifang, Sun Yanmei, the relationship between different delivery modes and pregnancy outcomes in the early stage of severe childbirth pain, Journal of Wuhan University Medical Edition 201426(09):205-255.
    54. Dou Xiaoqing, Fetal Umbilical Artery Doppler blood flow detection significance of Pregnancy Induced Hypertension in China Maternal and Child Health Care 2014:28(29):57-675.
    55. Fan Cuifang, Sun Yanmei, the relationship between different delivery modes and pregnancy outcomes in the early-onset of severe pre-eclampsia. Journal of Wuhan University Medical Edition 2014:26(09):205-255. [56] Comparison of short term prognosis between early-onset and late-onset severe pre-eclampsia in pregnant women, Huiyuan, Sun Lizhou Eastern Medicine 2014:45(45):670-690.
    56. Maternal Serum copeptin concentration in early-onset and late-onset preeclampsia. Abdullah Tuten et al. Taiwan J Obstet Gynecol Aug 2015, 54(4),350-4.
    57. Yingdong He et al. Expression of the Complement System’s Activation factors in plasma of patients with early-onset/late-onset severe pre-eclampsia.Am J Reprod Immunol. 2016:76(3):205-211.doi:10.1111/aji.12541.
    58. Hall DR, Odendaal HJ, Kriste GF. Smith J, Grove D. Expectant management of early-onset severe pre-eclampsia and perinatal outcomes. BJOG 2000:107(10):1258-1264.
    59. Hall DR, Odendaal HJ, Stegn DW, Grone D. Expectant management of early-onset severe preeclampsia maternal outcome. BJOG.2000;107(10):1252-1257.
    60. Hall DR, Grove D, Carstens E, Early Preeclampsia: What proportion of women qualify for expectant management and if not, why not? Eur J Obstet Gynecol Reprod Biol.2006;128(1-2):169-174. DOI:10.1016/j.ejogrb.2006.01.003.
    61. Espinoza J, Romero R, Nien JK, et al. Identification of patients at risk for early-onset and/or severe preeclampsia with the use of Uterine Artery Doppler Velocimetry and placental growth factor [published correction appears in Am J Obstet Gynecol 2007 Jun;196(6):614] Am J Obstet Gynecol. 2007;196(4):326.e1-326.13.doi:10.1016/j.ajog.2006.11.002.
    62. Masuyama H, Segawa T, et al. Different profiles of Circulating Angiogenic factors and adipocytokines between early-onset and late-onset preeclampsia. Bjog. 2009;117(3):314-320 DOI:10.1111/j.1471-0528.2009.20453.x
    63. Paerales A, Dalgado JL, de la Calle M, et al. sFlt-1/PIGF for prediction of early-onset preeclampsia: STEPS(Study of Early Preeclampsia in Spain) Ultrasound Obstet Gynecol .2017;50(3):373-382.doi:10.1002/uog.17373.
    64. Erez O. Romero R, Maynwn E, et al. The prediction of Late-onset pre-eclampsia: Results from a Longitudinal Proteomics Study. PLoS One. 2017;12(7):eo181468. Published 2017 Jul 24, DOI:10.1371/journal.pone.0181468.
    65. Aksorn Phusitaphong A, Phupong V. Risk factors for Early and late-onset preeclampsia. J Obstet Gynecol Res, 2012;39(3):627-631.doi:10.1111/j.1447-0756.212.02010.x.

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