Author : James Patrick C. Picar 1
Date of Publication :30th June 2023
Abstract: Prevalence of multidrug resistant (MDR) pathogens has increased with time due to various anthropologic and environmental factors. Because of this, a challenge that arose in the field of healthcare is to find a corresponding treatment for infections resistant to common antibiotics. Bacteriophage is a virus that kills bacteria and is known as an alternative treatment to multidrug resistant pathogens. This study focuses on the phenotypic characterization of the river water isolate bacteriophage against a well-known pathogen, Pseudomonas aeruginosa. Based on the stability test, the isolated phage is stable at both basic and acidic environment however showed a decrease in titer when exposed to higher alkalinity. The thermal stability test showed stability on cold and imitated body temperatures. The study highlights the phenotypic characteristics and lytic action of the isolated bacteriophage against Pseudomonas aeruginosa biofilm formation.
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